Allergic Inflammation—Innately Homeostatic
نویسندگان
چکیده
منابع مشابه
Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway
Notch is a pleiotropic signaling family that has been implicated in pathogenesis of allergic airway diseases; however, the distinct function of individual Notch ligands remains elusive. We investigated whether Notch ligands, Jagged1 and DLL4, exert differential effects in OVA-induced allergic asthma. We found that whilst Jagged1 inhibition mitigated Th2-dominated airway inflammation, blockage o...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2014
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a016352